Title: Sr. Research Associate
Duration: 12 Months
Location: Oceanside, CA 92056
 
Description
The employer is seeking a Sr. Research Associate I with hands-on experience in protein purification process development and process characterization. This role supports Process Development activities and contributes to biologics development projects in a collaborative, laboratory-based environment.
 
Essential Duties and Job Functions

• Plan and execute assigned on-site experiments in support of Process Development activities and project goals.
• Select appropriate experimental methods and techniques based on project requirements.
• Analyze and interpret experimental data, evaluate data quality, and identify anomalous results.
• Recommend alternative approaches, research new methods and techniques, and proactively consult senior team members to resolve technical challenges.
• Participate in group meetings and present experimental results, data interpretation, and conclusions.
• Demonstrate strong verbal communication and interpersonal skills, including the ability to clearly explain experimental processes and outcomes.
• Work collaboratively with a team-oriented, problem-solving mindset.
• Consistently follow safety practices; ability to work with highly potent compounds upon appropriate training.

 
Knowledge, Experience, and Skills

• Knowledge, Experience and Skills:
• Preferred degree in Chemical/Biochemical Engineering, Biochemistry, Chemistry or a related scientific discipline.
• Prior experience in biologics purification, with an emphasis on conjugation, tangential flow filtration (UF/DF), and filtration.
• Prior experience in analytical operations: SEC/HPLC, CE (R/NR), HCP testing is beneficial, but not required.
• Knowledge of cGMPs, technology transfer, and scaling up bioprocesses.
• Must be able to work effectively in cross-functional teams.
• Must demonstrate excellent technical writing skills.
• Working understanding of downstream process development including centrifugation, normal and tangential flow filtration, chromatography operations, and virus clearance. The ability to demonstrate hands on experience in several of these areas is expected. Experience with multiple modalities (mAbs, bispecifics, fusion and antibody drug conjugates, virus particles) produced in microbial and mammalian expression systems is a plus.
• Ability to work effectively within the purification team to help design and execute experiments supporting process definition, optimization, and characterization with an increasing level of independence.
• Ability to collaborate with Technical Operations during technology transfer from process development to GMP manufacturing, including serving as a process development representative during purification operations, providing technical troubleshooting and identifying opportunities for future process and equipment improvements. The candidate will also contribute to the preparation of regulatory filings and process validation and characterization reports.
• Ability to effectively communicate ideas, project goals and results and should have the ability to proactively identify issues and suggest solutions in a collaborative, multidisciplinary environment. This is a highly collaborative environment where willingness and ability to communicate and work effectively with individuals across various teams is essential.
• Self-motivated, organized, and enjoy scientific investigation and thinking. The candidate will monitor and contribute to external literature and scientific conferences.

 
Basic Qualifications

• BS degree in a relevant scientific discipline with 2+ years of relevant experience, OR
• MS degree in a relevant scientific discipline with 0+ years of relevant experience

 
 
At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $ 48.92/hr.