Position Title: Research Associate
Work Location: South San Francisco CA, 94080
Assignment Duration: 06 Month
Work Arrangement: Onsite
 
Position Summary: The primary responsibilities of the Biophysical Assay Research Associate will include performing analytical method development and testing samples using Capillary Electrophoresis, SDS-PAGE, DLS, MALS, AUC, and other analytical tools; contributing to design and performing experiments with supervision as needed; completing assigned tasks within time frames with high quality; maintaining a well-documented record of activities in lab notebook and reports. The position level will be commensurate with education and experience level. Additionally, the role includes regularly summarizing and presenting experimental results in lab meetings and being responsible for generating reports. This role will be at our organization location.
 
Background & Context: Characterizing adeno-associated viral nanoparticles for gene therapy products at our organization South San Francisco location.
 
Key Responsibilities:

• Conducting experiments to characterize adeno-associated viral nanoparticles for gene therapy products.
• Performing assays for particle/protein/DNA in multiple assays (Capillary Electrophoresis, SDS-PAGE, DLS, Western Blot, Light Obscuration, AUC, RP, SE – HPLC methods, etc.) to assist in evaluation of product characterization, including but not limited to: process change, formulation study, stability study using statistical methods as needed, following SOPs and execute experiments according to guidelines.
• Developing new assays and transfer to QC, Process Development, and Research.
• Developing new analytical tools to characterize adeno associated viral nanoparticles for gene therapy products
• Participating in writing, reviewing, and editing experimental procedures and reports
• Maintaining accurate records of all analytical development activities timely
• Analyzing and determining the applicability of laboratory data to draw conclusions and to make appropriate recommendations

 
Qualifications & Experience:

• Bachelor of Science with 2+ years of experience working in a pharmaceutical or biotech company and with the requisite years’ of experience employing the skills listed in the job description (for each level) performing multiple assays for bioproducts.
• Successful experience operating electrophoresis (CE, SDS-PAGE, alkaline gel, etc.), light scattering (DLS, MALS, etc.), UV/Vis spectrophotometry, or other technologies for protein/DNA-based product development.
• Strong knowledge and deep understanding of protein and DNA chemistry.
• Knowledge and proven experience in protein/DNA-based product development and characterization.
• Knowledge and expertise in principles and practice of current Good Manufacturing Practices (cGMP).
• Proficiency in Microsoft Office to include Excel, PowerPoint, and Word.
• Experience with recording experiments in electronic lab notebooks.
• Demonstrated verbal and written skills in technical reports and documents.
• Positive, professional self-starter with a passion for science.
• Proven ability to work collaboratively with effective communication in a team environment as well as being an individual contributor.
• Models our Core Values: Be Bold: Find a Way, Care Deeply, Get Stuff Done – is experienced as someone who exemplifies the culture we want to create; operates with transparency; is trusted.

May Have/Preferred:

• Direct, hands-on experience with adeno-associated viral nanoparticles.
• Experience operating chromatography methods (HPLC, etc.) and proficient understanding of chromatography software.
• Experience operating general ultracentrifugation methods.
• Experience operating PCR methods.
• Experience in analytical method development and assay transfer.
• Experience in statistical analysis with proficiency in statistical analysis software.

 
 
At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $ 31.00/weekly.