Position Title: Biologist
Work Location: Worcester, MA
Assignment Duration: 06 Months
Work Schedule: Monday–Friday, 9:00 AM–5:00 PM
Work Arrangement: Onsite
 
Position Summary:
The Quantitative, Translational ADME Sciences (QTAS) department is seeking a highly motivated and energetic bioanalytical scientist to join the biologics bioanalysis, characterization and proteomics (BBCP) group.
The primary responsibility of this position is to support LC-MS (liquid chromatography-mass spectrometry)-based bioanalysis and method development for biologic entities, such as monoclonal antibodies, multi-specific antibodies, antibody-drug conjugates (ADCs), and other novel modalities.
 
Key Responsibilities:

• Perform affinity purification and digestion of biological therapeutics (including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody-siRNA conjugates, and fusion proteins) from biological matrices manually or using automation systems.
• Operate and maintain LC/MS instruments to generate high-quality experimental data.
• Optimize and develop LC/MS methods to meet assay specificity and sensitivity requirements.
• Analyze data and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks.
• Communicate data interpretation internally and externally.

 
Qualifications & Experience:

• Degree in chemistry, pharmacology or other related fields. BS with 5+ years or MS with 2+ years in a pharmaceutical industry setting with a focus on mass spectrometry. Prior industry experience in drug discovery/development is highly desired.
• Highly motivated, self-driven and results-oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor.
• Hands-on experience with QQQ (SCIEX) is required, additional experience with qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers is a plus.
• Hands-on experience with biologics bioanalysis is highly desired, additional experience with oligonucleotide analysis is a plus.
• Hands-on experience with immuno-affinity purification and automation systems (e.g., TECAN, AssayMap Bravo or Hamilton) is highly desired.
• In-depth understanding of PK, TK and PK/PD studies is preferred.

 
 
At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $ 37.00/hr.