Job Description
Work Location: South San Francisco, CA
Assignment Duration: 12 Months
Work Arrangement: Onsite
Position Summary:
The Organization is seeking an outstanding Scientific Researcher to support formulation screening efforts within the Synthetic Molecule Pharmaceutical Sciences group. The successful candidate will contribute to the development and optimization of lipid nanoparticles (LNPs) and other parenteral formulations through high-throughput screening strategies and advanced analytical characterization. This role requires hands-on laboratory expertise, strong analytical skills, and the ability to work collaboratively within cross-functional teams to support pharmaceutical formulation development.
Key Responsibilities:
• Design and execute high-throughput formulation screening experiments for lipid nanoparticles (LNPs) and other parenteral drug delivery systems, using both bench instruments and automation tools.
• Physicochemical characterization of LNPs including particle size distribution, encapsulation efficiency, zeta potential, stability testing, etc.
• Solubility and stability screenings, solid state/polymorph characterizations to support formulation research and development.
• Design, plan, and troubleshoot laboratory experiments while maintaining strong attention to data quality and reproducibility.
• Analyze and interpret experimental data, generating clear reports, presentations, and summaries for project teams.
• Document experimental procedures and results in electronic laboratory notebooks (ELN) and internal data management systems.
• Collaborate with analytical scientists, formulation scientists, and cross-functional project teams to support development programs.
• Identify technical challenges and propose potential solutions to improve formulation performance and experimental workflows.
• Maintain compliance with laboratory safety standards, internal quality requirements, and regulatory guidelines.
Qualification & Experience:
• BS or MS degree in Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related scientific discipline.
• 1 - 5 years of industrial experience in pharmaceutical formulation research and development.
• Strong theoretical knowledge of pharmaceutics; analytical, physical, and/or organic chemistry.
• Hands-on experience with LNP formulation and analytics, including microfluidics, dialysis and ultrafiltration, particle sizing, encapsulation efficiency analysis.
• Self-motivated with strong problem-solving capabilities to design and execute experiments independently.
• Excellent written and verbal communication skills to work effectively in a collaborative team environment.
• Hands-on experience with analytical tools including UV/Vis/fluorescence spectroscopy, HPLC-UV/CAD/MS, capillary electrophoresis, or related technologies.
• Experience in analyzing peptides and nucleic acids.
• Experience with lab automation and hands-on experience with robotic liquid and solid handlers.
• Experience performing high-content data analysis, AI/ML, and interpreting complex experimental results.
- For information on benefits, equal opportunity employment, and location-specific applicant notices, click here
At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $ 45.00/hr.