Position Title: Process Development Associate
Work Location: Thousand Oaks, CA 91320
Assignment Duration: 12 Months
 
Position Summary: The Pre-Pivotal Drug Substance Technologies organization develops, characterizes, and supports clinical drug substance manufacturing processes for all early-stage programs in our organization’s portfolio.
 
Background & Context:

• This lab-based position is located at our Thousand Oaks, CA site.
• This role is in an integrated bioprocess development group in which cell culture and purification scientists work together to advance our organization’s rich, exciting, and dynamic pipeline.
• With our organization’s biology first approach, the position provides the unique opportunity to work on multiple modalities including antibodies, BiTEs, oncolytic viruses, bispecifics, and siRNAs.

 
Key Responsibilities:

• Support of the development, characterization, scale-up, and support of upstream and downstream processes to enable clinical advancement of our organization’s programs.
• Design and execute experiments at the bench scale, spanning the end-to-end drug substance process, including both cell culture and purification operations.
• Apply established platform approaches and utilize problem-solving skills to rapidly solve day-to-day experimental challenges.
• Utilize out-of-the-box thinking to contribute to technology development, including process automation.
• Expand and develop skills in both cell culture and purification, thereby further contributing to the integrated group.
• Work in a team environment to contribute to drug substance process development.
• Complete mammalian cell culture experiments at different scales in shake flasks and bioreactors.
• Implement purification experiments, mainly filtration and chromatography, at bench and pilot scale as needed.
• Document experimental data in lab notebooks.
• Analyze the data and present to the team.
• Author technical reports and support regulatory filing as needed.
• Contribute to technology development projects to seek continuous improvement in reliability and efficiency.

 
Qualification & Experience:

• Bachelor’s degree OR Associate’s degree and 2 years of experience OR High school diploma / GED and 4 years of experience.
• Degree in Chemical Engineering, Biochemistry, Biotechnology, Bioengineering, Biomedical Engineering, or Bioprocessing field or relevant experience in the pharmaceutical or related industry preferred.
• 1+ years of relevant hands-on industry lab experience in cell culture or protein purification (outside of education).
• Attention to details and critical thinking ability.

  
 
At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $ 25.00/hr.