Job Title – Sr. RA/Assoc. Sci, AAV Vector Biology and Molecular Optimization, Gene Delivery Process and Analytical Development Location: Seattle WA Duration: 12 months Pay rate starts from $55/hr Top Skills: • 2+ years of hands-on lab work on biotech industry • Experience in process development: Upstream process development and/or mammalian cell culture OR Downstream process development/purification • Bachelor's degree in STEM field
The senior research associate/associate scientist will join the Gene Delivery Process and Analytical Development (GDPAD) organization supporting process development, production, and characterization of viral vectors, which are critical to generating groundbreaking cell therapies.
The associate will join the AAV Platform Development team working on vector biology and molecular optimization initiatives intended to drive next-generation viral vector platform development. Specifically, in the pursuit of end-to-end assessment of novel technologies and approaches, the associate will seek to become highly proficient in upstream production and downstream purification of recombinant AAV, while gaining familiarity with AAV analytical methods and their interpretation in the context of AAV attributes and biology. The associate will also have the unique opportunity to be exposed to a wide range of highly novel molecular designs, and to work collaboratively with a range of different groups doing different types of rAAV development.
Responsibilities:
• Execute and troubleshoot upstream and downstream process development experiments supporting next-generation AAV production • Manage the flow of samples and data and perform analyses • Assist in the design of experiments and interpretation of data • Optimize workflows for assessing new constructs and modes of production • Provide experimental design and executional support to team members in adjacent and related functions (e.g. clinical development programs, high throughput process development, etc.) • Support research-to-development transition endeavors, including early-stage/pipeline molecular assessment activities • Actively participate and support lab maintenance and continuous improvement initiatives • Maintain accurate and detailed laboratory notebook and documentation • Summarize and present data in group meetings and contribute to group discussions and team strategy • Author technical reports and study memos
Basic Qualifications:
• STEM degree with 2+ years of relevant industry experience; title/compensation will ultimately be commensurate with education, experience, and skillset • Experience with suspension culture of mammalian cells in shake flasks and small stirred tank bioreactors • Hands on experience in process development • Independently motivated with ability to work in teams • Ability to communicate clearly and concisely through oral presentation and technical writing • Ability to leverage literature, internal and external resources to solve problems • Desire to identify and advance the cutting edge • Possess a growth mindset and the ability to thrive in a fast-paced, highly collaborative environment
Preferred Qualifications:
• Degree in biological or chemical engineering, biochemistry, or bio-related field • Hands-on experience in downstream purification including chromatography and filtration • Experience in the development of viral vectors (e.g. adeno-, retro-, lenti-), including successful transfer for GMP manufacturing • Experience with transfection-based processes • Experience with upstream processes intensification e.g. fed batch and perfusion development, process-analytical technology (PAT) • Experience with single-use technologies • Experience with late-stage development
Additional Job Requirements: Position Handles Hazardous Materials
Below is the brief introduction of SPECTRAFORCE, the benefits we offer and the disclaimers:
Established in 2004,SPECTRAFORCE is one of the largest and fastest-growing diversity-owned staffing firms in the US. The growth of our company is a direct result of our global client service delivery model that is powered by our state-of-the-art A.I. proprietary talent acquisition platform, robust ISO 9001:2015/ISO 27001 certified processes, and strong and passionate client engaged teams. We have built our business by providing talent and project-based solutions, including Contingent, Permanent, and Statement of Work (SOW) services to over 130 clients in the US, Canada, Puerto Rico, Costa Rica, and India. Key industries that we service include Technology, Financial Services, Life Sciences, Healthcare, Telecom, Retail, Utilities and Transportation.
SPECTRAFORCE is built on a concept of “human connection,” defined by our branding attitude of NEWJOBPHORIA®, which is the excitement of bringing joy and freedom to the work lifestyle so our people (and clients) can reach their highest potential. Our entire workflow and teams are trained to cultivate the joy of NEWJOBPHORIA® with candidates and employees throughout their engagement with SPECTRAFORCE. http://www.spectraforce.com
Benefits: SPECTRAFORCE offers ACA compliant health benefits as well as dental, vision, accident, and hospital indemnity insurances. Additional benefits SPECTRAFORCE offers to the eligible employees include commuter benefits, 401K plan with matching and a referral bonus program. SPECTRAFORCE offers unpaid leave as well as paid sick leave when required by law.
Equal Opportunity Employer: SPECTRAFORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, colour, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at nahr@spectraforce.com if you require reasonable accommodation.
About Us: Established in 2004, SPECTRAFORCE® is one of the largest and fastest-growing diversity-owned staffing firms in the US. The growth of our company is a direct result of our global client service delivery model that is powered by our state-of-the-art A.I. proprietary talent acquisition platform, robust ISO 9001:2015/ISO 27001 certified processes, and strong and passionate client engaged teams. We have built our business by providing talent and project-based solutions, including Contingent, Permanent, and Statement of Work (SOW) services to over 140 clients in the US, Canada, Puerto Rico, Costa Rica, and India. Key industries that we service include Technology, Financial Services, Life Sciences, Healthcare, Telecom, Retail, Utilities and Transportation. SPECTRAFORCE is built on a concept of “human connection,” defined by our branding attitude of NEWJOBPHORIA®, which is the excitement of bringing joy and freedom to the work lifestyle so our people and clients can reach their highest potential. Learn more at: http://www.spectraforce.com
Benefits: SPECTRAFORCE offers ACA compliant health benefits as well as dental, vision, accident, critical illness, voluntary life, and hospital indemnity insurances to eligible employees. Additional benefits offered to eligible employees include commuter benefits, 401K plan with matching, and a referral bonus program. SPECTRAFORCE provides unpaid leave as well as paid sick leave when required by law.
Equal Opportunity Employer: SPECTRAFORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at LOA@spectraforce.com if you require reasonable accommodation. At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $55.00/hr.
