Position Title: Scientist III - Biologics Developability Work Location: Worcester, MA 01068 Assignment Duration: 12 Months Work Arrangement: Onsite
Position Summary: The Biologics CMC Developability team is an integral part of the Biologics CMC Drug Product Development Org. The Biologics CMC Developability team is responsible for- (1) the identification of biophysical- and chemical liabilities in discovery-stage biologic drug candidates to guide lead selection, and (2) for characterization of the key CMC attributes important for biologic drug development. Background & Context: Contractor position supporting the Biologics CMC Developability team at our organization.
Key Responsibilities: • Perform in-depth LC-MS based characterization of therapeutic biologic molecules and their post-translational modifications. • Conduct liquid chromatography-based characterization of biologic drug candidates (size exclusion, ion exchange, and reverse phase). • Execute experimental protocols, collect results, and perform data analysis carefully and independently. • Maintain excellent documentation of work including electronic lab notebook and protocols. • Prepare and deliver concise scientific presentations of experimental results. • Oversee maintenance of key laboratory equipment and routine laboratory operations. • Build strong relationships with other team members and across groups. • Understand and adhere to corporate standards regarding code of conduct, safety, and documentation compliance.
Qualifications & Experience: • BS or MS in Biochemistry, Biology, Chemistry (or equivalent, e.g., Chemical Engineering, Pharmaceutical Sciences) with 5+ (BS) or 2+ years (MS), or Ph.D. with 0+ years of biopharmaceutical industry experience. • Hands-on experience with protein mass-spectrometry (subunit analysis, peptide mapping, disulfide mapping) and data processing is required. • Experience with liquid chromatography methods commonly used for characterization of biologic proteins is required. • Experience with liquid handling robots and their programming would be highly beneficial. • Demonstrated track record of independent thinking, creativity, and scientific accomplishment. • Highly responsible and self-motivated. Skills to plan and conduct experiments with high quality and timely deliverables. Able to perform data analysis using MS Excel & GraphPad. • Team player with excellent collaboration and communication skills.
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At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $ 60.00/hr.
