Job Title: Scientist I Location: Framingham, MA 01701 Duration: 12 months
Work Schedule
M-F 9AM-5PM
HM Notes:
Open to candidates willing to relocate at their own expense
Possibility of an extension
Experience:
For MS candidates, we are considering the required years (2-4) as professional work experience only in addition to the degree.
For PhD candidates, we would be open to consider non-doctoral research in academic settings or temporary industrial placements (Internships/Co-Op) as professional work experience.
**Must Have/Required Skills:
2+ years of pharma/biotech experience
Hands on experience/coursework/knowledge in mammalian cell culture process development: Experience with mammalian cell cultures (Experience with CHO cells, HEK cells, HeLa cells, CAR-T cells or T-cells, etc), therapeutic molecule production (enzymes, monoclonal antibodies, viral vectors, vaccines or cell therapy) and/or upstream process development (batch, fed-batch or perfusion cultures)
Coursework/knowledge and preferably past hands-on experience in bioreactor operation (bench scale and/or pilot scale stirred tank bioreactors or wave bioreactors)
**Nice to Have/Preferred Skills:
3+ years of relevant experience
Hands on experience/coursework/knowledge in Process Analytical Technology: Experience with sensor technology (spectroscopy, electrochemical, chromatographic or other), PAT applications (process monitoring or process control), or other.
Hands on experience/coursework/knowledge in Data Analytics: Potential experience with Statistical, Machine Learning or Deep Learning for regression in predictive models.
Description: As a scientist, the candidate will contribute to the development, characterization, testing, and scale-up/down of automated and PAT (Process Analytical Technology) enabled mammalian cell culture process platforms for biotherapeutic manufacturing. The goal of this position is to advance innovation in our manufacturing capabilities by developing robust, scalable, automated, and data-driven cell culture processes for diverse early and late-stage biologics pipeline. The candidate will work in a cross-functional environment and in close collaboration with members from the Cell Culture Development, Process Analytical Technology, Data Sciences, Automation Engineering, and Bioanalytics teams.
Key responsibilities: • Develop, characterize, and test an integrated and automated cell culture process platform and associated process strategies through the integration of sensing technology, data analytics and automation. • Investigate, design, and independently execute research activities using the aforementioned process platform to improve cell culture process performance (productivity and/or product quality), optimize platform workflows, and deepen scientific understanding of cell culture production systems. • Critically evaluate relevant scientific, technological, and regulatory literature to advance the proposed platform and its impact in our early and late-stage biologics pipeline. • Lead efforts for industrialization and technology transfer of proposed automated cell culture process platform and associated process strategies within. • Responsible for planning, executing, documenting, and interpreting experimental work and results with appropriate supervision and documentation. • Author high-quality scientific and operational documentation and deliver scientific presentations. Basic qualifications • Master’s degree (2-4 years) or PhD degree (0-2 years) in Biotechnology, (Bio)Chemical engineering, Biology, Biochemistry, or a related field. • Relevant knowledge, coursework and/or hands-on experience in mammalian cell culture process development (e.g., cell biology and biochemistry, cell culture engineering, recombinant protein production, bioreactor engineering, protein product characterization, sterility and aseptic techniques, technology transfer, etc.). • Strong motivation, curiosity, attention to detail, multitasking ability and active problem-solving and troubleshooting skills. • Ability to work both independently and in a team-oriented environment with strong project management and communication skills (oral/written).
Preferred Qualifications: • Relevant knowledge, coursework and/or hands-on experience in Process Analytical Technology (PAT), its applications (process monitoring, control, and supervision) and/or in-line/on-line sensing technology (e.g. Spectroscopy, Optical, Enzymatic, Chromatographic sensors, etc.) • Knowledge, coursework and/or hands-on experience in process data analytics (multivariate, time series and/or signal processing through statistical/machine learning methods).
About Us: Established in 2004, SPECTRAFORCE® is one of the largest and fastest-growing diversity-owned staffing firms in the US. The growth of our company is a direct result of our global client service delivery model that is powered by our state-of-the-art A.I. proprietary talent acquisition platform, robust ISO 9001:2015/ISO 27001 certified processes, and strong and passionate client engaged teams. We have built our business by providing talent and project-based solutions, including Contingent, Permanent, and Statement of Work (SOW) services to over 140 clients in the US, Canada, Puerto Rico, Costa Rica, and India. Key industries that we service include Technology, Financial Services, Life Sciences, Healthcare, Telecom, Retail, Utilities and Transportation. SPECTRAFORCE is built on a concept of “human connection,” defined by our branding attitude of NEWJOBPHORIA®, which is the excitement of bringing joy and freedom to the work lifestyle so our people and clients can reach their highest potential. Learn more at: http://www.spectraforce.com
Benefits: SPECTRAFORCE offers ACA compliant health benefits as well as dental, vision, accident, critical illness, voluntary life, and hospital indemnity insurances to eligible employees. Additional benefits offered to eligible employees include commuter benefits, 401K plan with matching, and a referral bonus program. SPECTRAFORCE provides unpaid leave as well as paid sick leave when required by law.
Equal Opportunity Employer: SPECTRAFORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at LOA@spectraforce.com if you require reasonable accommodation.
California Applicant Notice: SPECTRAFORCE is committed to complying with the California Privacy Rights Act (“CPRA”) effective January 1, 2023; and all data privacy laws in the jurisdictions in which it recruits and hires employees. A Notice to California Job Applicants Regarding the Collection of Personal Information can be located on our website. Applicants with disabilities may access this notice in an alternative format by contacting NAHR@spectraforce.com.
LA County, CA Applicant Notice: If you are selected for this position with SPECTRAFORCE, your offer is contingent upon the satisfactory completion of several requirements, including but not limited to, a criminal background check. We consider qualified applicants with arrest or conviction records for employment in accordance with all local ordinances and state laws, including the Los Angeles County Fair Chance Ordinance for Employers (FCO) and the California Fair Chance Act (FCA). The background check assessment will consider whether a criminal history could reasonably have a direct, adverse impact on the job-related safety, security, trust, regulatory compliance, or suitability for this role. Such findings may result in withdrawal of a conditional job offer.
At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $53.00/hr.
