Scientist
Spectraforce
South San Francisco, California
15 hours ago
Job Description
Title: Scientist
Duration: 06+ Months (Potential Extension)
Location: South San Francisco, CA, 94080
Description:
BS (1-3 years relevant experience) or MS in Biochemistry, Chemistry or Biology
General Position Summary/Purpose:
The Quantitative, Translational & ADME Sciences (QTAS) department is seeking a highly motivated fulltime contract Scientist to join the In Vitro ADME Sciences group (IVAS). The successful candidate will work in collaboration with other team members to characterize the CYP Induction properties of candidate drug molecules and may work on other in vitro ADME assays. QTAS works very closely with other disciplines (medicinal chemistry, pharmaceutical sciences, pharmacology, toxicology etc.) to conduct preclinical studies, support clinical evaluation and contribute to IND and NDA filings.
In this role, you will be a scientist with hands-on experience in conducting in-vitro ADME assays including CYP450 induction assays to characterize candidate drug molecules for potential to induce CYP450 enzymes. Furthermore, you will provide support to project teams to enhance mechanistic understanding of complex drug-drug interactions.
Core Job Responsibilities:
• Routinely conduct (hands-on) evaluation of CYP450 induction
• Conduct qPCR assay
• Interpretation of in vitro CYP induction data derived from assays in human hepatocytes or reporter gene systems
• Perform human and rodent hepatocytes cell culture, seeding and maintenance
• Perform cell viability assessments and use microplate reader to measure endpoints
• Contribute to the design of invitro ADME assays and data interpretation
• Analyze data and maintain detailed, accurate and comprehensible study documentations
• Use BioELN and GraphPad Prism for data analysis
About Us: SPECTRAFORCE is one of the fastest-growing workforce solutions firms in the United States. As a diversity-owned business, we place human connection at the heart of everything we do, building strong relationships with both clients and candidates to fill roles successfully. Our teams in North and Central America and India serve more than 150 Fortune clients globally, leveraging custom AI technology to provide direct hire, executive search, nearshoring, offshoring, and project staffing solutions.
Benefits: SPECTRAFORCE offers ACA compliant health benefits as well as dental, vision, accident, critical illness, voluntary life, and hospital indemnity insurances to eligible employees. Additional benefits offered to eligible employees include commuter benefits, 401K plan with matching, and a referral bonus program. SPECTRAFORCE provides unpaid leave as well as paid sick leave when required by law.
Equal Opportunity Employer: SPECTRAFORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at LOA@spectraforce.com if you require reasonable accommodation.
California Applicant Notice: SPECTRAFORCE is committed to complying with the California Privacy Rights Act (“CPRA”) effective January 1, 2023; and all data privacy laws in the jurisdictions in which it recruits and hires employees. A Notice to California Job Applicants Regarding the Collection of Personal Information can be located on our website. Applicants with disabilities may access this notice in an alternative format by contacting NAHR@spectraforce.com.
LA County, CA Applicant Notice: If you are selected for this position with SPECTRAFORCE, your offer is contingent upon the satisfactory completion of several requirements, including but not limited to, a criminal background check. We consider qualified applicants with arrest or conviction records for employment in accordance with all local ordinances and state laws, including the Los Angeles County Fair Chance Ordinance for Employers (FCO) and the California Fair Chance Act (FCA). The background check assessment will consider whether a criminal history could reasonably have a direct, adverse impact on the job-related safety, security, trust, regulatory compliance, or suitability for this role. Such findings may result in withdrawal of a conditional job offer.
At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $45.00/hr.
Duration: 06+ Months (Potential Extension)
Location: South San Francisco, CA, 94080
Description:
BS (1-3 years relevant experience) or MS in Biochemistry, Chemistry or Biology
General Position Summary/Purpose:
The Quantitative, Translational & ADME Sciences (QTAS) department is seeking a highly motivated fulltime contract Scientist to join the In Vitro ADME Sciences group (IVAS). The successful candidate will work in collaboration with other team members to characterize the CYP Induction properties of candidate drug molecules and may work on other in vitro ADME assays. QTAS works very closely with other disciplines (medicinal chemistry, pharmaceutical sciences, pharmacology, toxicology etc.) to conduct preclinical studies, support clinical evaluation and contribute to IND and NDA filings.
In this role, you will be a scientist with hands-on experience in conducting in-vitro ADME assays including CYP450 induction assays to characterize candidate drug molecules for potential to induce CYP450 enzymes. Furthermore, you will provide support to project teams to enhance mechanistic understanding of complex drug-drug interactions.
Core Job Responsibilities:
• Routinely conduct (hands-on) evaluation of CYP450 induction
• Conduct qPCR assay
• Interpretation of in vitro CYP induction data derived from assays in human hepatocytes or reporter gene systems
• Perform human and rodent hepatocytes cell culture, seeding and maintenance
• Perform cell viability assessments and use microplate reader to measure endpoints
• Contribute to the design of invitro ADME assays and data interpretation
• Analyze data and maintain detailed, accurate and comprehensible study documentations
• Use BioELN and GraphPad Prism for data analysis
About Us: SPECTRAFORCE is one of the fastest-growing workforce solutions firms in the United States. As a diversity-owned business, we place human connection at the heart of everything we do, building strong relationships with both clients and candidates to fill roles successfully. Our teams in North and Central America and India serve more than 150 Fortune clients globally, leveraging custom AI technology to provide direct hire, executive search, nearshoring, offshoring, and project staffing solutions.
Benefits: SPECTRAFORCE offers ACA compliant health benefits as well as dental, vision, accident, critical illness, voluntary life, and hospital indemnity insurances to eligible employees. Additional benefits offered to eligible employees include commuter benefits, 401K plan with matching, and a referral bonus program. SPECTRAFORCE provides unpaid leave as well as paid sick leave when required by law.
Equal Opportunity Employer: SPECTRAFORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at LOA@spectraforce.com if you require reasonable accommodation.
California Applicant Notice: SPECTRAFORCE is committed to complying with the California Privacy Rights Act (“CPRA”) effective January 1, 2023; and all data privacy laws in the jurisdictions in which it recruits and hires employees. A Notice to California Job Applicants Regarding the Collection of Personal Information can be located on our website. Applicants with disabilities may access this notice in an alternative format by contacting NAHR@spectraforce.com.
LA County, CA Applicant Notice: If you are selected for this position with SPECTRAFORCE, your offer is contingent upon the satisfactory completion of several requirements, including but not limited to, a criminal background check. We consider qualified applicants with arrest or conviction records for employment in accordance with all local ordinances and state laws, including the Los Angeles County Fair Chance Ordinance for Employers (FCO) and the California Fair Chance Act (FCA). The background check assessment will consider whether a criminal history could reasonably have a direct, adverse impact on the job-related safety, security, trust, regulatory compliance, or suitability for this role. Such findings may result in withdrawal of a conditional job offer.
At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $45.00/hr.