Job Description
Position Title: Computational Scientist
Work Location: South San Francisco, CA
Assignment Duration: 12 months
Work Schedule: Monday through Friday (weekend work as needed)
Work Arrangement: Fully onsite
Position Summary: We are seeking a highly motivated and collaborative Computational Scientist to join the Li Lab / Geiger-Schuller Lab / Regev Lab within our organization Research and Early Development (gRED). The successful candidate will derive actionable insights from high-content perturbation screens of ex vivo systems.
Background & Context: This role focuses on deriving actionable insights from high-content perturbation screens of ex vivo systems within our organization’s research environment.
Key Responsibilities: • Analyze large-scale high-content sequencing-based perturbation datasets • Collaborate with interdisciplinary and cross-functional teams including biologists, chemists, data scientists, and other stakeholders.
Qualification & Experience: • Educational Background: PhD degree in quantitative field (e.g., Computational Biology, Bioinformatics, Computer Science, Statistics, Mathematics) or in the physical or life sciences (e.g., Chemistry, Biology) with a strong quantitative focus. • Experience: • Proven track record of analyzing large-scale multi-conditional scRNA-seq datasets • Demonstrated interest in problems across biology and chemistry as applied to the discovery and development of treatments for disease. • Technical Skills: • Proficiency in scientific programming in Python. • Strong background in statistics, probabilistic modeling and data analysis. • Soft Skills: Excellent communication, collaboration, and problem-solving skills. • Publications: Strong publication record and experience contributing to research communities.
Preferred • Experience with the analysis of Perturb-seq/CROP-seq data, or more generally with CRISPR data • Multimodal data integration, in particular between multiple measurement modalities and/or clinical patient data • Experience with workflow managers such as nextflow or snakemake • Practical experience with working on HPC systems / SLURM
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At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position's pay range is $60.00/hr - $65.18/hr.