Position Title: Senior Scientist
Work Location: 01604, Worcester, MA
Assignment Duration: 06 Months
Work Arrangement: Onsite
 
Position Summary:
Immunology has discovery efforts focused on the development of humanized complex in vitro models (CIVMs) to support our ongoing projects focused on Rheumatoid Arthritis. We are seeking a bench scientist with extensive in vitro skills who can develop, maintain and execute on quantitative endpoint assays for CIVMs such as organ-on-a-chip.
 
Background & Context:
The role is within Immunology Discovery and is a bench role requiring onsite work.
 
Key Responsibilities:

• Routine culture and maintenance of cell lines and primary cell cultures in standard formats as well as in organ-on-a-chip format. Prior experience with these systems and with a variety of cell types including fibroblasts, endothelial cells and immune cells is highly desirable
• Assessment of endpoints from CIVMs including qPCR, MSD, immunofluorescence, viability and cytotoxicity to evaluate therapeutic efficacy
• In depth characterization of CIVMs including transcriptomics and proteomics to understand clinical translatability of the model
• Excellent written and oral communication skills, including data analysis, record keeping in an electronic notebook and presentation of work at project team meetings

Qualifications & Experience:

• Preference for PhD or equivalent education with less then 4 years of experience. Bachelor’s Degree or equivalent education and typically 12 years of experience, Master’s Degree or equivalent education and typically 10 years of experience
• Experience working with primary, diseased cells in multi-cellular assay formats
• Experience with standard cell and molecular biological assays such as ELISA/MSD, qPCR, immunofluorescence staining, imaging, viability and cytotoxicity assays
• Experience demonstrating therapeutic effects in cell-based systems
• Excellent communication and collaboration skills
• Preference given to candidates with prior drug discovery/industry and CIVM experience

 
 
At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $ 62.00/hr.