Position Title: Research Associate II

Work Location: South San Francisco, CA, 94080

Assignment Duration: 1 year (possible extension)

Work Schedule: M–F, 9am–5pm

Work Arrangement: Full-time, lab-based

Position Summary:

• The Advanced Cell Engineering (ACE) Hub in the Cell Therapy department is seeking a talented and enthusiastic candidate for a full-time lab-based Research Associate II contractor position.

• The ACE Hub is an interdisciplinary team with a mission to accelerate drug discovery in gRED through the development, application, and enablement of genome engineering and synthetic biology technologies.

Background & Context:

• The successful candidate will support the needs of the ACE Hub, particularly in the engineering and profiling of cells for cell therapy development and disease modeling used across the organization.

• They will be expected to work independently and make technical contributions within a dynamic, fast-paced, and highly collaborative research environment.

• This is a one-year position with the possibility of extension.

Key Responsibilities:

• Generate engineered cells (including cancer cell lines, iPSCs, and primary cells) using stable integration (both lentivirus and piggybac) and CRISPR gene editing

• Transfection/gene editing optimization

• Troubleshoot cell engineering protocols

• Characterize engineered cells using genomics and molecular assays

• Maintain and quality check cell lines in culture

Qualification & Experience:

• A self-motivated candidate with a (BS/MS) + 3 years industry experience, or PhD in Molecular Biology, Cell Biology, Genetics, or a related discipline

• Qualified candidates must have demonstrable strong mammalian cell culture techniques and ability to generate high-quality data

• Excellent written and verbal communication skills; required to analyze and present data at team meetings

• Team-oriented, highly organized both operationally and in silico, with the ability to multi-task across a diverse array of projects, and eager to learn new skills

• Ready to start ASAP

Other Preferred Qualifications:

• Prior experience with primary T cells and iPSCs

• Prior expertise in some or all of the following: DNA/RNA/Protein extraction and quantification, molecular cloning, PCR, RT-PCR, ddPCR assay design and screening, FACS, transfection, CRISPR genome editing, siRNA/shRNA, SDS-PAGE, immunoblotting, cell-based assays, NGS, and viral vector development/use

• Experience with sequence/data analysis platforms such as Benchling, Snapgene, FlowJo, GraphPad Prism desirable

 
 
At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $ 58.00/hr.