Research Associate II
Spectraforce
South San Francisco, California
18 days ago
Job Description
Job Title: Research Associate II
Job Location: South San Francisco, CA, 94080
Job Duration: 3 Years Assignment
Note: Worker needed onsite 5 days a week.
About Us: SPECTRAFORCE is one of the fastest-growing workforce solutions firms in the United States. As a diversity-owned business, we place human connection at the heart of everything we do, building strong relationships with both clients and candidates to fill roles successfully. Our teams in North and Central America and India serve more than 150 Fortune clients globally, leveraging custom AI technology to provide direct hire, executive search, nearshoring, offshoring, and project staffing solutions.
Benefits: SPECTRAFORCE offers ACA compliant health benefits as well as dental, vision, accident, critical illness, voluntary life, and hospital indemnity insurances to eligible employees. Additional benefits offered to eligible employees include commuter benefits, 401K plan with matching, and a referral bonus program. SPECTRAFORCE provides unpaid leave as well as paid sick leave when required by law.
Equal Opportunity Employer: SPECTRAFORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at LOA@spectraforce.com if you require reasonable accommodation.
California Applicant Notice: SPECTRAFORCE is committed to complying with the California Privacy Rights Act (“CPRA”) effective January 1, 2023; and all data privacy laws in the jurisdictions in which it recruits and hires employees. A Notice to California Job Applicants Regarding the Collection of Personal Information can be located on our website. Applicants with disabilities may access this notice in an alternative format by contacting NAHR@spectraforce.com.
LA County, CA Applicant Notice: If you are selected for this position with SPECTRAFORCE, your offer is contingent upon the satisfactory completion of several requirements, including but not limited to, a criminal background check. We consider qualified applicants with arrest or conviction records for employment in accordance with all local ordinances and state laws, including the Los Angeles County Fair Chance Ordinance for Employers (FCO) and the California Fair Chance Act (FCA). The background check assessment will consider whether a criminal history could reasonably have a direct, adverse impact on the job-related safety, security, trust, regulatory compliance, or suitability for this role. Such findings may result in withdrawal of a conditional job offer.
At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $43.00/hr.
Job Location: South San Francisco, CA, 94080
Job Duration: 3 Years Assignment
Note: Worker needed onsite 5 days a week.
Department; Peptide Therapeutics Department | Early Discovery Biochemistry
Description:
Description:
Position Summary:
We are seeking a highly motivated contractor to support discovery efforts in the Macrocycle Discovery Group within the Peptide Therapeutics Department. The successful candidate will contribute to the identification of novel macrocyclic peptides using in vitro selection platforms and will play a key role in assay development, high-throughput screening, and data analysis for early drug discovery programs.
Key Responsibilities:
Conduct in vitro selection campaigns using mRNA and/or phage display technologies to discover active macrocyclic peptides targeting high-priority therapeutic proteins.
Handle phage libraries, including amplification, titration, panning, and rescue procedures.
Design and execute ELISA-based binding assays for hit validation and screening.
Utilize laboratory automation and high-throughput screening (HTS) techniques to enable efficient assay setup, sample processing, and reagent preparation.
Analyze next-generation sequencing (NGS) results using internal bioinformatics tools to identify early hits and guide selection campaign progression.
Test the incorporation and expression of non-canonical amino acid monomers to enhance library diversity through genetic code expansion.
Maintain and manage complex reagent inventories used across multiple preclinical discovery platforms.
Collaborate cross-functionally with scientists in biochemistry, screening, and informatics to support project goals and timelines.
Qualifications:
B.S., M.S., or equivalent degree in Biochemistry, Molecular Biology, Chemical Biology, or a related discipline with relevant lab-based experience.
Hands-on experience with in vitro display technologies, particularly mRNA display and/or phage display (including phage propagation and selection).
Proficiency in ELISA, western blot, and high-throughput screening methods.
Familiarity with NGS data analysis and experience with laboratory automation platforms.
Strong attention to detail, excellent organizational skills, and ability to work both independently and as part of a collaborative team.
Top 3 Skills
Curious and wants to learn Ability to pay attention to details Collaboration (ability to work with others)
We are seeking a highly motivated contractor to support discovery efforts in the Macrocycle Discovery Group within the Peptide Therapeutics Department. The successful candidate will contribute to the identification of novel macrocyclic peptides using in vitro selection platforms and will play a key role in assay development, high-throughput screening, and data analysis for early drug discovery programs.
Key Responsibilities:
Conduct in vitro selection campaigns using mRNA and/or phage display technologies to discover active macrocyclic peptides targeting high-priority therapeutic proteins.
Handle phage libraries, including amplification, titration, panning, and rescue procedures.
Design and execute ELISA-based binding assays for hit validation and screening.
Utilize laboratory automation and high-throughput screening (HTS) techniques to enable efficient assay setup, sample processing, and reagent preparation.
Analyze next-generation sequencing (NGS) results using internal bioinformatics tools to identify early hits and guide selection campaign progression.
Test the incorporation and expression of non-canonical amino acid monomers to enhance library diversity through genetic code expansion.
Maintain and manage complex reagent inventories used across multiple preclinical discovery platforms.
Collaborate cross-functionally with scientists in biochemistry, screening, and informatics to support project goals and timelines.
Qualifications:
B.S., M.S., or equivalent degree in Biochemistry, Molecular Biology, Chemical Biology, or a related discipline with relevant lab-based experience.
Hands-on experience with in vitro display technologies, particularly mRNA display and/or phage display (including phage propagation and selection).
Proficiency in ELISA, western blot, and high-throughput screening methods.
Familiarity with NGS data analysis and experience with laboratory automation platforms.
Strong attention to detail, excellent organizational skills, and ability to work both independently and as part of a collaborative team.
Top 3 Skills
Curious and wants to learn Ability to pay attention to details Collaboration (ability to work with others)
About Us: SPECTRAFORCE is one of the fastest-growing workforce solutions firms in the United States. As a diversity-owned business, we place human connection at the heart of everything we do, building strong relationships with both clients and candidates to fill roles successfully. Our teams in North and Central America and India serve more than 150 Fortune clients globally, leveraging custom AI technology to provide direct hire, executive search, nearshoring, offshoring, and project staffing solutions.
Benefits: SPECTRAFORCE offers ACA compliant health benefits as well as dental, vision, accident, critical illness, voluntary life, and hospital indemnity insurances to eligible employees. Additional benefits offered to eligible employees include commuter benefits, 401K plan with matching, and a referral bonus program. SPECTRAFORCE provides unpaid leave as well as paid sick leave when required by law.
Equal Opportunity Employer: SPECTRAFORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at LOA@spectraforce.com if you require reasonable accommodation.
California Applicant Notice: SPECTRAFORCE is committed to complying with the California Privacy Rights Act (“CPRA”) effective January 1, 2023; and all data privacy laws in the jurisdictions in which it recruits and hires employees. A Notice to California Job Applicants Regarding the Collection of Personal Information can be located on our website. Applicants with disabilities may access this notice in an alternative format by contacting NAHR@spectraforce.com.
LA County, CA Applicant Notice: If you are selected for this position with SPECTRAFORCE, your offer is contingent upon the satisfactory completion of several requirements, including but not limited to, a criminal background check. We consider qualified applicants with arrest or conviction records for employment in accordance with all local ordinances and state laws, including the Los Angeles County Fair Chance Ordinance for Employers (FCO) and the California Fair Chance Act (FCA). The background check assessment will consider whether a criminal history could reasonably have a direct, adverse impact on the job-related safety, security, trust, regulatory compliance, or suitability for this role. Such findings may result in withdrawal of a conditional job offer.
At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position’s starting pay is: $43.00/hr.